Last Updated on June 11, 2025
Soliris is a critical treatment for people living with rare and life-threatening conditions. But the high cost of the drug can make filling your prescription feel overwhelming. Insurance restrictions, out-of-pocket costs, and eligibility rules only add to the confusion.
NeedyMeds is here to help you cut through the noise. We connect people to trusted programs that make medications like Soliris more affordable, no matter your insurance status.
In this blog, we’ll walk you through several ways to reduce the cost. If you’re looking for Soliris copay help or patient assistance programs, you’re in the right place.
What is Soliris?
Soliris (eculizumab) is a prescription biologic used to treat several rare and serious conditions, including:
- Generalized Myasthenia Gravis (gMG)
- Atypical Hemolytic Uremic Syndrome (aHUS)
- Paroxysmal Nocturnal Hemoglobinuria (PNH)
- Neuromyelitis Optica Spectrum Disorder (NMOSD)
It works by targeting a part of your immune system called the complement system, helping to reduce damage caused by uncontrolled immune activity. Soliris is administered through intravenous (IV) infusion, typically every two weeks after a loading period.
Because it is used for rare and serious diseases, Soliris is one of the most expensive drugs on the market, with yearly treatment costs that can exceed $500,000. This makes cost-saving options absolutely essential.
Why is Soliris So Expensive?
Soliris is a biologic medication, meaning it is made using living cells through a complex and costly manufacturing process.
While the original patent expired in 2021, Alexion holds additional patents through 2027. A legal settlement allowed Amgen to launch the first biosimilar, Bkemv, in April 2025, offering a potentially lower-cost alternative. Still, until biosimilars gain widespread adoption, the cost of treatment remains high for many patients.
Because of these costs, Alexion offers several financial support programs to help eligible patients access Soliris. Whether you have commercial insurance, Medicare, or no coverage at all, their OneSource platform can help reduce or even eliminate out-of-pocket expenses. We will walk through those programs in the next sections.
Soliris Manufacturer Assistance Programs
If you take Soliris and have commercial insurance or no insurance at all, you may be eligible for financial support through Alexion’s OneSource platform. This program offers different types of assistance depending on your insurance coverage and financial situation.
To apply, you’ll need to:
- Download the OneSource Patient Enrollment Form with your personal and insurance information
- Include copies of the front and back of your insurance and pharmacy cards
- Check copay consent (if signing up for the copay assistance program)
- Submit the form by email, fax, or mail using the contact details provided on the form
Enrolling in OneSource also connects you with a case manager who can help determine if you qualify for free medication through the Patient Assistance Program.
As always, we encourage patients to check out our Soliris Coupon Page, as we frequently update it with the current offers available.
Is Soliris Covered Under Medicare?
Soliris is typically covered under Medicare Part B, since it is administered by infusion in a clinical setting. While coverage is available, many patients still face high out-of-pocket costs, especially without supplemental insurance.
One option to consider is Medicare Extra Help, also known as the Low-Income Subsidy program. This program is primarily for medications covered under Part D but can reduce overall drug-related expenses for people with limited income and assets.
To qualify in 2025, your income must generally be below $22,590 (or $30,660 for couples), with limited resources. If approved, Extra Help can lower monthly premiums, deductibles, and copays for prescription drugs.
You can apply through the Social Security Administration or by calling 1-800-772-1213.
Patient Access Network Foundation (PAN)
If you are living with Myasthenia Gravis and take Soliris, you may be eligible for financial assistance through the PAN Foundation. This nonprofit organization helps underinsured patients with Medicare afford their out-of-pocket medication costs.
Their Myasthenia Gravis fund allows eligible patients receive up to $10,100 per year. At the end of the eligibility period, you may apply for additional assistance, depending on available funding.
To qualify, you must meet all of the following criteria:
- Be receiving treatment for myasthenia gravis
- Reside and receive treatment in the United States or U.S. territories (U.S. citizenship is not required)
- Have Medicare insurance that covers your prescribed medication
- Be prescribed a drug listed on PAN’s covered medications list
- Have a household income at or below 500 percent of the Federal Poverty Level
Financial assistance is awarded on a first-come, first-served basis and funding availability may vary. If the fund is temporarily closed, you can sign up for email or text alerts on the PAN Foundation website to be notified when the program reopens.
Final Thoughts
For people with rare conditions, Soliris can be a life-saving treatment. But its cost does not have to be a barrier to access.
Whether you have insurance, are enrolled in Medicare, or are currently uninsured, there are programs available to help reduce or eliminate out-of-pocket expenses.
If you are unsure what programs you qualify for, NeedyMeds can help. Visit our website to explore our free resources, or call our Helpline at 800-503-6897 for personalized support.
