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There has been a lot in the news lately about aducanumab (Aduhelm), a new monoclonal antibody treatment for Alzheimer’s disease. Alzheimer’s disease is a neurological disease and is the most common cause of dementia. It causes destructive, progressive, and irreversible changes in the brain. A common feature is the accumulation of a protein called amyloid-β in the form of plaques and tau tangles. Both are thought to cause cell death, but they have not yet been shown to be the cause of Alzheimer’s disease. Aducanumab (Aduhelm), a drug that reduces amyloid-β plaques, was approved by the FDA on […]
Alzheimer’s disease is a neurological disease that is the most common cause of dementia. It causes progressive destructive and irreversible changes in the brain. A common feature is the accumulation of a protein called amyloid-β in the form of plaques and tau tangles. Both are thought to cause brain cell death. Although among the most likely candidates, they have not yet been shown to be the cause of Alzheimer’s disease. In a blog from 2 years ago a newly approved drug for Alzheimer’s disease named aducanumab was discussed. At the time I thought the medication had not been proven to […]