Major depression, also commonly referred to as clinical depression, is one of the most common mental illnesses in the United States. Major depression, including major depressive disorder, manic depression, and dysthymia, affect more than 19 million Americans a year. Almost two-thirds of those with depression are women. The symptoms of clinical depression vary, but common symptoms include persistent sad or anxious mood, sleeping issues, reduced appetite, irritability, fatigue, and thoughts of suicide among others. From Mental Health America, “Depression causes people to lose pleasure from daily life, can complicate other medical conditions, and can even be serious enough to lead to suicide.”

There are many causes of major depression, and each case is different. “For some people, a number of factors seem to be involved, while for others a single factor can cause the illness. Oftentimes, people become depressed for no apparent reason.” One common reason is biological, having too many or too few neurotransmitters in the brain. However, genetics, medication

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