Why do kids have unfilled prescriptions?

You take your sick child to the doctor. An exam is done, a diagnosis made, a prescription written, and instructions given to the parent. The next step: a trip to the pharmacy to have the prescription filled so the child can start the medicine as soon as possible. Right? Why, then, did a recent study reveal that up to 25% of children’s prescriptions remain unfilled?

02.27Investigators are currently examining whether electronic prescriptions are filled more often (because the patient does not have the opportunity to lose or misplace it), or if, in fact a written prescription serves as a tangible reminder to go to the pharmacy to get the prescription filled.

Other researchers are looking at the rate of prescriptions being filled as a result of a well-child visit versus that of a sick-child visit. Some early findings are showing that prescriptions given at sick-child visits are filled more often than those given at well-child visits.

For the uninsured and underinsured, the costs of prescription medications can be daunting. Even for those who have health insurance, co-pays and deductibles mean that many still struggle to afford the costs of their medications. Yet not taking medication as prescribed can also lead to emergency room visits, hospitalizations and other medical interventions that are even more costly.

Safety net resources may be available for those who are unable to afford the costs of their medications. In a future blog entry, we will introduce those to our readers.

To Vaccinate, Or Not?

The development of vaccines to protect against potentially killer diseases likes polio, measles and pertussis (whooping cough) has been widely hailed as one of the crowning achievements of medicine in the 20th century.  As the table below shows, the incidence of these, and other diseases, decreased by between 95-100% once vaccines were given. Many of us can likely remember hearing stories of family members who died from these diseases, or who were otherwise seriously and permanently affected from having suffered from these diseases. But are we taking this standard of care for granted?

According to a recent study reported by Reuters, “Nearly half of babies and toddlers in the United States aren’t getting recommended vaccines on time – and if enough skip vaccines, whole schools or communities could be vulnerable to diseases such as whooping cough and measles.”vaccine

We are seeing the effects of “under-vaccination” already as outbreaks of pertussis (whooping cough) are becoming increasingly common. Medical researchers have discovered that boosters are necessary to keep immunity at proper levels for adults, especially pregnant women. The Centers for Disease Control and Prevention website is an excellent resource that provides guidelines for infants, children and adults. Evidence-based, scientific studies have proven the efficacy and safety of these vaccines, and there have been no studies to date that reveal vaccines to cause any harm. Still, some parents appear to believe that their children are better off without them, and one study revealed that “one in eight children went under-vaccinated due to parents choices,” (Reuters).

What do you think? Do you vaccinate your children? We would love to hear your views on this important subject.

Your Good Health: Medication Adherence

Last month, many of us made New Year’s resolutions and we were being deluged with advice about how to eat sensibly, how to exercise our way to fitness, and how to develop and keep healthy habits. But let’s get down to basics: how well do you follow your doctor’s advice?

Doctors will be increasingly held accountable for your overall health and wellness, and your progress towards sustained good health, under the Affordable Care Act (ACA). The ACA aims to increase the quality of care given and reduce the costs, thereby ensuring that the right care is given in the right place at the right time. More care has not proven to be better care, and reducing unnecessary and expensive screens and tests will go a long way to reducing health care costs.

But patients have a responsibility too – and that is to listen to your physician and follow their recommendations regarding nutrition, exercise and taking your medications as prescribed. “Medication adherence” or “medication compliance” are terms used to describe what patients do once they receive a prescription from their provider, including filling, and then re-filling when indicated, taking the prescribed dose in the prescribed manner for the prescribed duration, and promptly reporting any symptoms or side effects to their provider.

02.20Adult Meducation is a good resource on medication adherence. It maintains “Medications are arguably the single most important healthcare technology to prevent illness, disability, and death in the older population. Of all age groups, older persons with chronic diseases and conditions benefit the most from taking medications, and risk the most from failing to taken them properly.” Consequences of nonadherence could be serious and lead to hospital admissions, falls, and preventable deaths.

Why don’t some people comply with their prescribed medications? Some cannot afford them. Some may be too confused to remember to take them. Some may feel they are not working and discontinue them. Fierce Healthcare reports that medication adherence improves with better doctor-patient communication.  The patient-physician relationship is the single best predictor for medication compliance. Case management, education, decision aids, and reminder systems are also important factors.

One step many patients don’t take is discussing their medication regime with their physician. Not just the drugs taken, but how and when they are taken. For example, if one medicine is to be taken four times a days and another three times a day, is there a way to take two pills three times a day and the fourth pill once. Or perhaps a dosage change in the four-times-a-day pill would result in taking it only three times a day?

Another issue is that certain pills must be taken on an empty stomach while others should be taken with food. If a morning pill must be taken one hour before eating, then breakfast has to be delayed. Add in a pill that has to be taken one hour after eating and the schedule gets very complicated.

Patients should make their doctors aware of all the medicines they are taking and when they take them. Let the doctors know of issues encountered and ask if the schedule can be simplified.  As always clarity and communication with your doctor is key.

What Does “Off-Label” Mean?

We often hear about drugs being prescribed “off-label.” Many patients have questions about what this means. Is it safe? Is it legal? How can we know that off-label use will help us get better?

Off-label use is the practice of prescribing pharmaceuticals for an unapproved indication, age group, dose or form of administration. We will explain more about this shortly.

But first, let’s look at how drugs are approved for use in our country.

In the U.S., the Food and Drug Administration Center for Drug Evaluation and Research review’s a company’s New Drug Application for data from clinical trials to see if the results support the drug for a specific use or indication.

pillbottleIf the drug is found to be safe and effective, it can be marketed for the specific condition for which it was approved by the FDA.  Until recently, however, it was against FDA regulations for pharmaceutical companies or their representatives to market a drug for any conditions for which the FDA hadn’t approved.  A recent federal appeals court decision now allows physicians and other healthcare providers to prescribe the medication for uses other than the specific FDA-approved indication.

That difference is important because it begs the question: Is there science behind off-label use? That is, why would a provider prescribe a medication for a different use? Often, there is anecdotal evidence that a medication turns out to be useful for a different condition.  Over time, physicians, and providers, through their own experiences, and those of their colleagues, may feel an off label use would be beneficial to their patients in certain circumstances.

Some examples of off-label use include:

  • The use of tricyclic antidepressants to treat neuropathic pain;
  • The use of bupropion, brand name Wellbutrin, as a smoking cessation drug.

The recent court ruling may change this landscape and allow off label promotion under the Freedom of Speech provision.  Will we now see drugs marketed for their off-label use?  What about Patient Assistance Programs – will patients be able to apply for an off-label diagnosis?  We will keep you posted!

Do You E-mail Your Doctor?

Just about everyone seems to be online these days. Communication with family and friends via email and social media outlets including Facebook and Twitter, as well as texting appear to be replacing telephone calls and letter writing. We wonder what we may be losing in this shift: is our privacy being compromised? Are these news methods of communicating enhancing the depth of our interactions, or are they just surface? And what happens with our medical care?

Do you email your doctor? Would you want to? In late November, a new survey revealed that patients want digital engagement with their healthcare providers. Fierce Healthcare (11/29/12) reported on a survey that sought to examine types of relationships between patients and providers including how often, and through which channels they prefer to communicate. Called “Engaging the Healthcare Consumer and Improving the Patient Experience,” Varolii and the Patient-Centered Primary Care Collaborative (PCPCC)  report that the majority of consumers would embrace mobile interaction, like email and text messages, but few providers are reaching out to patients through these preferred channels. They also mention that patients with chronic conditions, such as diabetes, see the most benefit from being able to communicate with their provider and monitor their heath through mobile channels and smartphone web apps. They recommend that providers pay more attention to smartphone owners who are developing different patterns of engagement than other patients.

E-mailWhat do the doctors think? Does electronic communication compromise patient privacy and patient safety? Are their potential malpractice issues that need to be considered? Is face-to-face doctor/patient time still the gold standard? Would electronic communication be compensated? These questions, and others, need to be discussed and addressed by physician groups, and studies on this model need to be conducted and data analyzed, before we can definitively answer these questions.

Electronic communication is faster, more efficient & less costly.  In this era of healthcare reform, both providers and patients are looking for high quality health care at the lowest possible costs and best use of resources.  Many times, people head for the emergency department or urgent care when they are suffering from a bad cold or persistent cough. New electronic services, available for a subscription fee, mean that they can interact with the medical provider from the comfort of their homes with a click of a button- as long as they have the right equipment. A computer, webcam and Internet access is all that is needed in most instances.

This method is probably best used for more common, easily treated ailments rather than complex or chronic diseases, but it does represent a new modality of healthcare, and one I think we will definitely be seeing more often!